Pentosan Polysulfate 250 mg/ml – solution 20 ml
research-grade
solution
in a glass bottle. Pentosan polysulfate (PPS) is a sulfated xylan–derived polysaccharide explored in laboratory models of glycosaminoglycan (GAG) biology, extracellular-matrix interactions and growth-factor binding.
Research Use Only:
All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.
Purity
High-purity research grade
Content
250 mg/ml PPS; 20 ml per bottle (total 5,000 mg per bottle)
Packaging
20 ml glass bottle with secure cap
Storage
Store at 2–8 °C; protect from light. Do not freeze.
Molecular identity
Sulfated xylan polymer (glycosaminoglycan mimetic)
Average MW
Polydisperse polymer mixture (manufacturer-dependent)
CAS number
37319-17-8 (sodium pentosan polysulfate)
Research Overview
Pentosan polysulfate is a sulfated polysaccharide used as a tool compound to interrogate glycosaminoglycan-like interactions with extracellular-matrix components and growth factors. In vitro and in vivo laboratory systems employ PPS to study heparan-sulfate–mimetic binding, surface-charge shielding, urothelial GAG-layer models, and anti-inflammatory signaling pathways under controlled experimental conditions.
Primary Research Areas
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GAG/ECM interactions:
Binding to ECM proteins and proteoglycans; modulation of surface charge in model systems.
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Growth-factor binding:
Heparan-sulfate–like interactions affecting FGF/VEGF availability in cell-based assays.
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Urothelial barrier models:
Experimental GAG-layer reconstruction and permeability endpoints.
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Inflammatory signaling:
In vitro cytokine and complement-related readouts under defined conditions.
