Cardarine (GW-501516) 10 mg – 60 capsules research-grade capsule formulation supplied in a sealed bottle. Cardarine (GW-501516) is a synthetic, highly selective agonist of the peroxisome proliferator-activated receptor delta (PPARδ) studied in experimental models of lipid metabolism, endurance capacity, glucose homeostasis and cardiovascular function.
Research Use Only: All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.
Purity
High purity (HPLC, third-party tested)
Content
10 mg Cardarine (GW-501516) per capsule; 60 capsules per bottle
Packaging
Sealed bottle with tamper-evident closure
Storage
Store at room temperature, protected from light; keep desiccated.
Molecular formula
C21H18F3NO3S2
Molecular weight
≈ 453.5 g·mol⁻¹
IUPAC name
{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid
Research Overview
Cardarine (GW-501516) is a synthetic ligand that functions as a potent and selective agonist of the nuclear receptor PPARδ. In experimental systems, activation of PPARδ by Cardarine is used to explore transcriptional programs involved in fatty acid oxidation, energy expenditure, endurance capacity and cardiometabolic regulation across a range of in vitro and in vivo research models.
Primary Research Areas
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PPARδ receptor activation: Used as a tool compound to selectively activate PPARδ and dissect downstream gene expression programs related to lipid utilization, mitochondrial function and energy homeostasis.
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Fatty acid oxidation and lipid metabolism: Studied in preclinical models to evaluate how PPARδ agonism alters fatty acid uptake, β-oxidation, plasma lipids and tissue-specific lipid handling in metabolic research settings.
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Endurance and exercise-capacity models: Applied in experimental frameworks that investigate skeletal muscle substrate selection, oxidative capacity and performance-related endpoints following PPARδ activation.
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Glucose homeostasis and insulin sensitivity: Employed in models of glucose regulation to explore interactions between lipid oxidation, glucose uptake, insulin signaling and overall glycemic control.
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Cardiovascular and vascular function: Used in cardiovascular research to study endothelial signaling, vascular inflammation and cardiometabolic risk markers under conditions of experimental PPARδ agonism.
