Snap-8 10 mg
research-grade
lyophilized peptide powder
supplied in a glass vial. Snap-8, also known as
Acetyl Octapeptide-3,
is an elongated analog of Acetyl Hexapeptide-8 (Argireline) based on the N-terminal domain of the SNAP-25 protein and
studied for its interaction with the SNARE complex in cosmetic science and neurobiological research models.
Research Use Only:
All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.
Purity
High-purity research grade
Form
Lyophilized peptide powder
Content
10 mg Snap-8 (Acetyl Octapeptide-3) per vial
Packaging
Glass vial with sterile closure
Storage
Store lyophilized at 2–8 °C (desiccated, protect from light)
Molecular formula
C41H70N16O16S
Molecular weight
~1075.2 g·mol⁻¹
Sequence
Acetyl-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC).
For a compatible research-only solvent, see
Bacteriostatic water – 10 ml
.
Research Overview
Snap-8 (Acetyl Octapeptide-3) is a synthetic octapeptide derived from the N-terminal region of the SNAP-25 protein, a key component
of the SNARE complex involved in regulated vesicle fusion and neurotransmitter release. In in vitro and in vivo laboratory models,
Snap-8 is used to investigate how competitive interaction with SNAP-25 may modulate SNARE complex assembly, catecholamine release
and neuromuscular signaling pathways that are of interest in cosmetic science wrinkle-reduction research and related mechanistic studies.
Primary Research Areas
-
SNARE complex modulation:
used in studies examining how Acetyl Octapeptide-3 may compete with SNAP-25 for incorporation into the SNARE complex and how this
affects vesicle docking and fusion events in neurosecretory systems.
-
Catecholamine and acetylcholine release:
applied in experimental models evaluating potential changes in vesicular catecholamine and acetylcholine release from neurons and
neuromuscular junction preparations under controlled conditions.
-
Muscle contraction signaling pathways:
incorporated into research exploring presynaptic modulation of neuromuscular signaling cascades, focusing on mechanisms relevant to
muscle contraction and relaxation cycles in cosmetic and neurophysiological models.
-
Cosmetic science wrinkle models:
used as a tool compound in in vitro skin and tissue models designed to study anti-wrinkle strategies based on neuromuscular signaling
modulation and SNARE complex targeting approaches.
-
Comparison with Acetyl Hexapeptide-8:
evaluated alongside Acetyl Hexapeptide-8 (Argireline) in comparative studies on sequence length, SNARE interaction, signaling impact
and model outcomes in cosmetic science research.
