Dermorphin 5 mg
research-grade
lyophilized peptide powder
in a glass vial. Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist studied in experimental models of opioid receptor pharmacology, GPCR/cAMP signaling, nociception and neurobiology.
Research Use Only:
All products are intended exclusively for laboratory and scientific research. Not for human or veterinary use.
Purity
High-purity research grade
Form
Lyophilized peptide powder
Content
5 mg Dermorphin per vial
Packaging
Glass vial with sterile closure
Storage
Store lyophilized at 2–8 °C in a dry, desiccated place, protected from light.
Molecular formula
C40H50N8O10
Molecular weight
≈ 802.9 g·mol⁻¹
Sequence
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (7 aa)
In laboratory workflows, lyophilized research peptides are typically handled with suitable sterile diluents such as bacteriostatic water (BAC).
For a compatible research-only solvent, see
Bacteriostatic water – 10 ml
.
Research Overview
Dermorphin is a frog-derived heptapeptide employed as a tool compound in μ-opioid receptor research. In experimental systems it is used to probe MOR selectivity and potency, downstream Gi/o-coupled GPCR signaling, cAMP inhibition, β-arrestin pathways, and mechanisms underlying nociception and neuroplasticity in vitro and in vivo laboratory models.
Primary Research Areas
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Opioid receptor pharmacology (MOR): Binding selectivity, efficacy and signaling bias in receptor assays.
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GPCR signaling & cAMP/β-arrestin pathways: Gi/o-mediated signaling, second-messenger dynamics and receptor internalization.
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Nociception & sensory neurobiology: Laboratory models of pain pathway modulation and spinal/central processing.
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Peptide chemistry & stability: Structure-activity relationships for D-Ala–containing opioid peptides.
