SR-9009 is a synthetic compound known as a Rev-Erbα nuclear receptor agonist that is being investigated for its potential effects on circadian rhythms, fat metabolism, energy expenditure, and mitochondrial activity. In this formulation, SR-9009 is dissolved in MCT oil for research use.
This professional text is for educational and research purposes only. It does not constitute a recommendation for human use.
What is SR-9009?
SR-9009 is an experimental synthetic molecule that acts as an agonist of Rev-Erbα receptors, a component of the biological clock that regulates circadian rhythms. It is being investigated for its potential effects on metabolic processes, energy expenditure, inflammatory responses, and lipid metabolism. Interestingly, SR-9009 was developed to “biochemically mimic” the effects of exercise.
How does SR-9009 work?
SR-9009 activates nuclear receptors Rev-Erbα, which play a role in the synchronization of the internal biological clock. By activating these receptors, SR-9009 affects the expression of genes responsible for fat metabolism, glucose and mitochondrial biogenesis. The result is increased energy expenditure, reduced cholesterol production and improved metabolic balance - without direct stimulation of the central nervous system.
Researched effects and interesting facts
- Increased energy expenditure at rest and during exercise (rodent studies).
- Reducing triglycerides, LDL cholesterol and blood glucose levels.
- Suppression of inflammatory markers such as TNF-α and IL-6.
- Impact on the circadian rhythm of sleep and wakefulness.
- Potential in obesity and metabolic syndrome research.
Dosage in studies
The data below is from preclinical research and does not constitute a recommended dosage.
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Dosage: 20–100 mg daily
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Form of submission: intramuscular (MCT oil)
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Frequency: 1–2 times a day
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Duration: 2–12 weeks depending on protocol
This content is not intended as a dosage recommendation. It is for research and informational purposes only.
Possible side effects
- Nausea or indigestion (when taken orally).
- Decreased appetite.
- Fatigue or decreased energy with long-term administration.
- Stomach irritation (at higher doses).
Resources
- Solt et al., 2012 – Nature Medicine: Regulation of Circadian Behavior by Rev-Erb Agonists
- Banerjee et al., 2013 – SR9009 Enhances Metabolism in Skeletal Muscle
- PubChem CID: 49852112 – SR-9009
All information provided is for informational purposes only and is based on available scientific studies. The product is not approved for human use.
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