Selank is a synthetic peptide derived from the endogenous tetrapeptide tuftisin, which has been researched to have nootropic, anxiolytic, and neuroprotective properties. It is characterized by its ability to influence monoamine levels in the CNS and regulate the expression of neurotrophic factors.
Concentration (test)
11.64 mg ± 0.05 mg
Packaging
Glass bottle with sterile cap
Storage
2–8 °C, away from light
Molecular formula
C33H57N11O9
Molecular weight
751.9 g mol⁻¹
IUPAC name
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Other names
TP-7, tuftsin analog
In laboratory conditions, Selank is used in research:
- improving cognitive functions and memory,
- reduction of anxiety and stress response,
- regulation of serotonin and dopamine levels,
- supporting neuroplasticity and BDNF expression,
- modulation of immune response and anti-inflammatory activity.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.
What is Selank?
Selank is a synthetic heptapeptide derived from the natural tetrapeptide tuftisin. It is classified as a nootropic and anxiolytic peptide in research. Its mechanism of action includes influencing the metabolism of monoamines (dopamine, serotonin, noradrenaline), increasing the expression of neurotrophins (especially BDNF), and influencing the immune system.
In experiments, improvements in cognitive performance, stabilization of emotions, and reduction of anxiety reactions without sedative effects were observed.
How Selank works
Selank affects the GABAergic system, monoamine levels and the expression of neurotrophic factors. By increasing BDNF levels, it promotes neuroplasticity, neuronal regeneration and CNS resistance to stress. Compared to traditional anxiolytics, it does not have sedative or muscle-relaxant effects.
Selank also affects the balance of Th1/Th2 cytokines, which is associated with immunomodulatory properties.
Samples examined
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Improved memory and attention: Increased synaptic plasticity and BDNF activity in the hippocampus.
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Reduction of anxiety: Mechanism similar to benzodiazepines, but without the side effects.
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Neuroprotection: Protection against oxidative stress and neurotoxicity.
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Immunomodulation: Normalization of T-helper cell balance.
Dosage in studies
The values listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
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Dosage: 200 – 500 mcg daily
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Form: subcutaneous
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Frequency: 1–2 times a day
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Duration: 7 – 30 days according to protocol
Possible side effects
- Mild itching or dryness in the nose with intranasal administration
- Injection site irritation with subcutaneous administration
- Rarely, headache or dizziness
Resources
- Andreeva et al. (2006). Neuropsychotropic activity of Selank
- Kolomin et al. (2017). Selank increases BDNF expression
- Levitskaya et al. (2013). Study of Selank's effect on the immune system
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is intended for educational purposes.
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