PE22-28 - 5mg

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PE22-28 - 5mg

€34,99
€49,99
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30% OFF

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1,800+ Verified Orders!

PE22-28 - 5mg

€34,99
€49,99
30% OFF
30% OFF

Third Party Tested

14-Day Money Back Guarantee

Fast Delivery Worldwide

PE-22-28 is a synthetic peptide developed as an analogue of a natural neuropeptide associated with neuroprotective and behavioral effects. It is being studied in the laboratory for its potential in neurodegenerative diseases and anxiolytic mechanisms.

Parameters
Value
Form
Lyophilized powder
Contents
5mg ± 5%
Concentration (test)
98% purity (HPLC)
Packaging
Glass vial for research purposes
Storage
2–8°C, protect from light
Molecular formula
C61H98N16O13
Molecular weight
1227.52 g mol⁻¹
IUPAC name
Unspecified
CAS number
1931968-93-2
Other names
PE22-28
  • research into neuroprotection and regeneration of nervous tissue,
  • analysis of behavioral and anxiolytic effects,
  • investigation of neurodegenerative mechanisms,
  • modulation of synaptic plasticity,
  • impact on adaptive responses to stress.

This professional text is for educational and research purposes only. It does not constitute a recommendation for human use.

What is PE-22-28?

PE-22-28 is a synthetic derivative of the endogenous peptide spexin that has been modified to increase its stability and bioavailability. It is being investigated in laboratory studies for its neuroprotective and anxiolytic properties. Its actions are the subject of ongoing research in the field of neurological diseases and behavioral disorders.

How does PE-22-28 work?

The mechanism of action of PE-22-28 is not yet fully understood, but it is believed to affect G-protein receptors in the central nervous system. In this way, it may modulate neurotransmission, neuroinflammation, and neuroplasticity. It is being studied for its ability to reduce anxiety and improve cognitive function in various models of stress and neurodegeneration.

Effects studied

  • Neuroprotection in oxidative stress experiments.
  • Anxiolytic effects without sedative effects.
  • Improving neuroplasticity and synaptic adaptation.
  • Potential significance in Alzheimer's disease and depression.
  • Regulation of stress response and behavioral abnormalities.

Dosage in studies

The data below are from preclinical studies in animal models. They do not represent recommended dosages for humans.

  • Dose: 50–300 μg/kg daily
  • Administration form: subcutaneous or intramuscular injection
  • Frequency: 1× daily
  • Duration: 7–28 days depending on protocol

This content is not intended as a dosage recommendation. It is for research and informational purposes only.

Possible side effects

  • Local irritation at the injection site.
  • Rarely, headaches or nausea.
  • Potential behavioral changes at higher doses.
  • Reversible changes in motor skills in susceptible subjects.
  • No serious systemic effects have been reported.

Resources

  • Li et al., 2020 – Effects of PE-22-28 in rat models of anxiety
  • Journal of Peptide Science, 2019 – Synthetic analogs of spexin
  • NCBI PubChem – PE-22-28 compound summary

All information provided is for educational purposes only. The product is not intended for human use. Injection into a vein (intravenous) is expressly not recommended .

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Warning

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.

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