Livagen is a short peptide from the class of bioregulators derived from liver tissues. It is being studied in the laboratory for its effects on cell regeneration, epigenetic regulation, and cytoprotection against oxidative stress.
Concentration (test)
21.53 mg ± 0.05 mg
Packaging
Glass bottle with sterile cap
Storage
2–8 °C, away from light
Molecular formula
Unspecified
Molecular weight
Unspecified
Other names
Liver peptide, cytomedin liver
- regulation of gene expression in liver cells,
- cytoprotection and antioxidant mechanisms,
- epigenetic restoration of damaged tissues,
- potential effect on regeneration after toxic damage,
- studying the effects of peptide therapy in chronic liver diseases.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.
What is Livagen?
Livagen is a short peptide bioregulator obtained from liver tissue, which is used in regenerative medicine research. It belongs to the group of so-called cytomexins - tissue-specific peptides that bind to chromatin and affect gene transcription. Its effect is observed primarily in liver cells and cells with high oxidative stress.
How does Livagen work?
Livagen penetrates the cell nucleus, where it interacts with DNA and modulates gene expression. Its epigenetic effect is being investigated in particular, in which it can suppress the expression of pro-inflammatory and pro-apoptotic genes, while activating regenerative and antioxidant pathways. In experiments, increased growth and regeneration of damaged liver cells were noted.
Effects studied
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Liver cell regeneration: Supporting the restoration of functional hepatocytes after toxic or ischemic damage.
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Epigenetic modulation: Modification of the expression of genes responsible for inflammation, apoptosis, and cellular differentiation.
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Antioxidant protection: Reducing the level of reactive oxygen species (ROS) in cells.
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Cytoprotection: Increasing resistance to environmental and metabolic stressors.
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Neurodegeneration research: A possible role in protecting neurons is being investigated in experimental models.
Dosage in studies
The values listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
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Dose: 0.5 – 5 mg daily
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Form: subcutaneous or intramuscular
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Frequency: 1x daily or every other day
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Duration: 10 – 30 days
Possible side effects
- Mild irritation or redness at the injection site
- Transient fatigue or drowsiness
- Rarely reported mild digestive upset
Resources
- Khavinson, V. et al. (2003). Peptide bioregulators in gerontology and anti-aging medicine
- International Journal of Peptide Research (2020). Peptides and gene expression modulation
- Journal of Bioregulatory Medicine (2021). Hepatic cytoprotective peptides and epigenetic mechanisms
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is for educational purposes only.
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