GHK-Cu is a naturally occurring peptide complex with a copper ion that is being studied in scientific studies for its regenerative, anti-inflammatory and anti-aging properties. It is of significant interest in the areas of tissue healing, hair growth stimulation and skin renewal.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.
What is GHK-Cu?
GHK-Cu is a copper-bound tripeptide that occurs naturally in human plasma and tissues. It consists of glycine, histidine, and lysine, binding copper in a 1:1 ratio. It has been associated with various regenerative and rejuvenating effects in the literature, leading to its investigation in the fields of dermatology, orthopedics, and hair restoration.
How GHK-Cu works
The GHK peptide binds copper and transports it to tissues, where it is involved in activating repair and regeneration processes. It regulates the expression of hundreds of genes related to extracellular matrix repair, inflammation, and oxidative stress. In some studies, improvements in angiogenesis, collagen synthesis, and hair follicle repair have been observed.
Researched effects and interesting facts
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Skin regeneration: accelerated healing of wounds, burns and scars
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Hair stimulation: activation of hair follicle growth
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Anti-inflammatory effect: reduction of cytokines and oxidative stress
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Collagen restoration: support for ECM and synthesis of collagen types I and III
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Anti-aging effect: improving skin elasticity and hydration
Dosage in studies
The values listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
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Dose: 100 – 500 μg daily
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Form: subcutaneous or intramuscular
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Frequency: 1x daily or every other day
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Duration: 2 – 6 weeks depending on the goal
Possible side effects
- Irritation or swelling at the injection site
- Temporary skin discoloration (due to copper)
- Mild itching or dryness of the skin
- No systemic toxicity when used topically or injected in studies
Resources
- Pickart, L. et al. (2015). GHK-Cu: Biological effects and clinical implications
- Campbell, L. et al. (2012). The effects of copper peptides on skin and hair regeneration
- Ahmed, S. et al. (2020). Copper tripeptide as a regenerative agent
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is for educational purposes only.
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