Epitalon is a synthetic tetrapeptide that was developed based on the natural peptide epithalamine produced by the pineal gland. It is being studied in scientific experiments mainly for its effects on cell cycle regulation, telomerase activation and potential cell lifespan extension.
Contents
10 mg (measured 5.98 mg in test sample)
Packaging
Glass vial with cap
Storage
Out of reach of light, at a temperature up to 8 °C
Molecular formula
C14H22N4O9
Molecular weight
390.35 g mol⁻¹
IUPAC name
L-alanyl-L-glutamyl-L-asparaginyl-glycine
Other names
Epithalamine, Ala-Glu-Asp-Gly
In laboratory studies, Epitalon is associated with research in areas such as:
- telomerase activation and telomere elongation,
- supporting cell stability and longevity,
- antioxidant and neuroprotective effects,
- normalization of the pineal rhythm (melatonin),
- potential effects in the area of healthy aging.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.
What is Epitalon?
Epitalon is a synthetic analogue of the natural pineal peptide epithalamine. It is composed of four amino acids – alanine, glutamic acid, asparagine and glycine – and is among the research peptides studied in relation to telomerase regulation and potential modulation of the aging process.
How Epitalon works
The mechanism of action of Epitalon is being investigated in the context of its effect on the activation of the enzyme telomerase – an enzyme that lengthens telomeres, the protective ends of chromosomes. Telomere shortening is associated with aging and cell apoptosis. In addition, its neuroprotective, antioxidant and immunomodulatory properties are also being investigated.
Effects studied
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Telomerase and telomeres: Activation of telomerase and slowing of telomere shortening in cell cultures.
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Neuroprotection: Protection of neurons from oxidative stress and improvement of cognitive parameters in animals.
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Sleep rhythm and melatonin: Epitalon has an effect on circadian rhythm and melatonin levels.
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Immune balance: Potential immunomodulatory effects with long-term administration in experiments.
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Cellular renewal: Promoting cell renewal and reducing the frequency of apoptosis in some studies.
Dosage in studies
The values listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
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Dosage: 1–5 mg daily
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Form: intramuscular or subcutaneous
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Frequency: 1× daily
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Duration: 10–20 days according to research protocol
Possible side effects
- Mild irritation at the application site
- Temporary fatigue or drowsiness
- Rarely reported headaches
Resources
- Khavinson, V. et al. (2003). Peptide Epitalon activates telomerase and elongates telomeres in human somatic cells
- Korkushko, OV et al. (2006). Epithalamin effects on biological age and lifespan
- Khavinson, V. Kh. (2002). The role of peptide bioregulators in aging and longevity
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is for educational purposes only.
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