BPC-157 is a synthetic peptide derived from a protein fragment found in human gastric secretion. It has been scientifically studied for its regenerative and anti-inflammatory properties, particularly in the areas of tissue healing and vascular repair.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.
What is BPC-157?
BPC-157 (Body Protective Compound) is a synthetic peptide composed of 15 amino acids, derived from a protein naturally present in human gastric secretion. It is being studied in the scientific literature for its potential to accelerate the regeneration of various types of tissues, including muscles, ligaments, tendons, the nervous system, and blood vessels.
At the molecular level, it is a stable pentadecapeptide, the biological activity of which has been tested primarily in animal models. Results indicate its ability to promote angiogenesis, regulate inflammatory processes, and improve cellular renewal in various body systems.
How BPC-157 works
BPC-157 acts primarily through interaction with endothelial and neural receptors. It increases the expression of VEGF (vascular endothelial growth factor), thereby promoting healing and vascularization of injured tissues. In some models, it has been shown to regulate oxidative stress and reduce TNF-α and IL-6.
Effects have also been observed in the gastrointestinal tract, where it supports mucosal repair and ulceration regeneration. In the nervous system, its effects on neuronal protection and stress resilience are being investigated.
Researched effects and interesting facts
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Tissue regeneration: accelerated healing of tendons, muscles, ligaments and bones
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Angiogenesis: promoting the formation of new blood vessels and improving circulation in damaged areas
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Anti-inflammatory effects: reduction of inflammation and oxidative stress in both local and systemic conditions
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GIT protection: restoration of the gastric mucosa and prevention of ulcerations
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Neuroregeneration: potential for peripheral nerve regeneration and neuroprotective effects
Dosage in studies
The values listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
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Dose: 200 – 800 μg daily
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Form: subcutaneously or intramuscularly, locally
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Frequency: 1–2 times a day
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Duration: 2 – 4 weeks according to protocol
Possible side effects
- Local irritation or swelling at the application site
- Individual sensitivity to peptide sequences
- No known systemic toxic effects.
Resources
- Sikiric, P. et al. (2018). BPC 157 and its potential in tissue healing and organ protection
- Sikiric, P. et al. (2020). Stable gastric pentadecapeptide BPC 157: From healing to biological roles
- Chang, CH et al. (2011). Effect of BPC 157 on tendon healing
- Gwyer, D. et al. (2022). Potential regenerative peptides in muscle and nerve healing
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is for educational purposes only.
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