ARA-290 - 10mg

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ARA-290 - 10mg

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€49,99
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1,800+ Verified Orders!

ARA-290 - 10mg

€29,99
€49,99
40% OFF
40% OFF

Third Party Tested

14-Day Money Back Guarantee

Fast Delivery Worldwide

ARA-290 is a synthetic peptide derived from erythropoietin (EPO), investigated for its regenerative and anti-inflammatory effects without stimulating erythropoiesis. In preclinical research, it is being tested mainly in the areas of neuroprotection, tissue healing and chronic pain relief.

Parameters
Value
Form
Lyophilized powder
Contents
10 mg
Concentration (test)
Unspecified
Packaging
Glass bottle with cap
Storage
2–8 °C, away from light
Molecular formula
C147H243N43O39
Molecular weight
3270.8 g mol⁻¹
IUPAC name
Unspecified
CAS number
105184-37-0
Other names
Cibinetide, ARA 290

In laboratory studies, ARA-290 is associated with research in areas such as:

  • protection of peripheral nerves and reduction of neuropathic pain,
  • tissue regeneration without stimulation of hematopoiesis,
  • reducing inflammation and oxidative stress,
  • restoration of microcirculation and capillary flow,
  • investigation in diabetic neuropathy and ischemic models.
This content is for educational purposes only. It is not a recommendation for human use. The substance is intended for laboratory research only.

What is ARA-290?

ARA-290 is a synthetic peptide derivative of erythropoietin, designed to retain the regenerative and anti-inflammatory effects of EPO without stimulating red blood cell production. It aims to activate cytoprotective mechanisms without the risk of increased blood viscosity or erythrocytosis.

How ARA‑290 works

ARA-290 binds to the receptor complex composed of EPOR and CD131 (the so-called innate repair receptor – IRR). This triggers intracellular signaling pathways related to tissue repair, inflammation reduction and neuroprotection. However, it does not activate the EPOR dimer, which is responsible for erythropoiesis – thus avoiding the adverse hematological effects of classic EPO.

Researched effects and interesting facts

  • Neuroprotection: reduction of neuropathic pain and inflammation in peripheral nerves
  • Vascular regeneration: support of capillary flow and endothelial balance
  • Anti-inflammatory effect: suppression of TNF-α, IL-6 and oxidative markers
  • Tissue protection: effects observed in ischemic and diabetic models
  • Without hematological stimulation: does not affect hemoglobin levels or erythropoiesis

Dosage in studies

The values ​​listed are derived solely from research studies and are not intended for real-world use outside of a laboratory environment.
  • Dose: 100 – 900 μg daily
  • Form: subcutaneous
  • Frequency: 1× daily
  • Duration: 1 – 4 weeks depending on the protocol

Possible side effects

  • Mild irritation at the injection site
  • Transient fatigue or drowsiness
  • Rarely reported nausea
  • Without stimulation of hematopoiesis and hematocrit

Resources

  • Brines, M. et al. (2008). Erythropoietin derivatives protect against tissue injury
  • Carreno, F. et al. (2016). ARA-290 and neuropathic pain relief
  • Ransohoff, RM et al. (2014). Innate repair receptor activation by non-erythropoietic EPO derivatives
This article is for informational purposes only. It does not constitute a recommendation or solicitation for use. The information provided is a summary of existing scientific literature and is for educational purposes only.

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Warning

This product is not intended for human or veterinary use. It is for collection or research purposes only. It cannot be used as food, dietary supplement or medicine! The information provided in the text on this page is for educational purposes only and does not constitute medical or other advice.

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